Medicinal Plants as Potential Antiviral Agents in HIV Therapy

Mwende Muthoni D.

Faculty of Medicine Kampala International University Uganda

ABSTRACT

Despite the progress in antiretroviral therapy (ART), the emergence of drug resistance and side effects necessitates alternative approaches to HIV treatment. This review examines the potential of medicinal plants as sources of novel anti-HIV agents. Bioactive compounds such as flavonoids, terpenoids, and alkaloids have demonstrated antiviral properties through diverse mechanisms, including inhibition of viral replication and modulation of host immune responses. We discuss preclinical and clinical studies, challenges in standardization, and the synergistic potential of plant-based treatments with conventional therapies. Emphasis is placed on the need for rigorous clinical trials, multidisciplinary research, and ethical considerations to advance the development of plant-derived anti-HIV agents. This work highlights the promising role of traditional medicine in addressing gaps in HIV management.

Keywords: Medicinal plants, HIV therapy, Antiviral agents, Bioactive compounds, Traditional medicine.

CITE AS: Mwende Muthoni D. (2024). Medicinal Plants as Potential Antiviral Agents in HIV Therapy. RESEARCH INVENTION JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES 4(3):23-26. https://doi.org/10.59298/RIJSES/2024/432326