Gene Editing with CRISPR: Ethical and Clinical Implications                           

Kamanzi Ntakirutimana G.

School of Natural and Applied Sciences Kampala International University Uganda

ABSTRACT

CRISPR-Cas9 gene editing has revolutionized genetic research and clinical applications by offering unprecedented precision and potential for treating previously incurable diseases. However, this technology raises significant ethical, legal, and societal concerns, particularly in the context of human clinical trials. This paper examines the ethical dilemmas posed by CRISPR, including inheritable genetic modifications, regulatory challenges, and safety concerns related to off-target effects. It also explores current and future clinical applications, regulatory frameworks, and case studies illustrating the moral complexities of using CRISPR for therapeutic purposes. In conclusion, the responsible development of CRISPR technology must balance innovation with ethical safeguards to protect humanity from unforeseen consequences.

Keywords: CRISPR-Cas9, Gene editing, Ethical implications, Clinical applications, Inheritable genetic modification.

CITE AS: Kamanzi Ntakirutimana G. (2024). Gene Editing with CRISPR: Ethical and Clinical Implications. RESEARCH INVENTION JOURNAL OF BIOLOGICAL AND APPLIED SCIENCES 3(3):21-24