Novel Biomarkers for Early Detection of Neurodegenerative Diseases using Liquid Biopsy

Okafor, Azubuike Ikechukwu and Emuru, Edward Odey

Department of Medical Biochemistry, University of Cross River State, Calabar, Nigeria

Email: okafor.azubuike@gmail.com; phone number: +2348035723454

ABSTRACT

Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Amyotrophic lateral sclerosis (ALS), represent a significant global health challenge, exacerbated by the aging population. Early detection is critical to improving patient outcomes, but current diagnostic methods are invasive, costly, and not conducive to large-scale screening. Liquid biopsy, a minimally invasive technique analyzing biofluids like blood, presents a promising alternative for early detection through novel biomarkers. This paper explores the potential of liquid biopsy for identifying early-stage biomarkers in neurodegenerative diseases, discussing the emerging biomarkers, the challenges in their validation, and the future direction of this technology in clinical applications.

Keywords: Neurodegenerative Diseases, Liquid Biopsy, Early Detection, Biomarkers, Alzheimer’s Disease.

 CITE AS: Okafor, Azubuike Ikechukwu and Emuru, Edward Odey (2023). Novel Biomarkers for Early Detection of Neurodegenerative Diseases using Liquid Biopsy. RESEARCH INVENTION JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES 2(1):1-5.