Comprehensive Overview of Alcohol Intoxication: Mechanisms, Effects, and Interventions
1Joseph Obiezu Chukwujekwu Ezeonwumelu, 2Uhama Kingsley Chukwuka, 3Ugwu
Okechukwu Paul-Chima, 3Alum Esther Ugo, 4Ugwuanyi Anthony Chukwudi and 5Tambwe Patrick Rodrigue
1Department of Clinical Pharmacy and Pharmacy Practice, Kampala International University Western Campus, Uganda.
2Department of Biochemistry, Faculty of Applied Natural Sciences, Enugu State University of Science and Technology, Nigeria.
3Department of Publication and Extension Kampala International University Uganda.
4Department of Microbiology Ebonyi State University Abakaliki, Nigeria.
5Department of Public Health Kampala International University Uganda.
Email: kingsley.uhama@esut.edu.ng
ABSTRACT
Alcohol intoxication, a reversible state of diminished brain responsiveness due to alcohol consumption, poses significant public health challenges worldwide. This review delineates the biological, psychological, and social mechanisms underlying alcohol intoxication, emphasizing blood alcohol concentration (BAC) thresholds for clinical diagnosis. The prevalence and sociocultural influences on alcohol consumption are examined alongside the pharmacokinetics and pharmacodynamics of ethanol. Acute and chronic health consequences, including impaired motor and cognitive functions, liver disease, cardiovascular effects, and mental health issues, are discussed in detail. Finally, this review explores prevention and treatment strategies, highlighting public health interventions and therapeutic approaches aimed at mitigating the adverse effects of alcohol intoxication. This comprehensive analysis underscores the need for multidisciplinary efforts to address the complex interplay of factors contributing to alcohol intoxication and its widespread impact.
Keywords: Alcohol intoxication, Blood alcohol concentration, Psychotropic effects, Acute and chronic health consequences, Public health interventions, Therapeutic approaches
CITE AS: Joseph Obiezu Chukwujekwu Ezeonwumelu, Uhama Kingsley Chukwuka, Ugwu Okechukwu Paul-Chima, Alum Esther Ugo, Ugwuanyi Anthony Chukwudi and Tambwe Patrick Rodrigue (2024). Comprehensive Overview of Alcohol Intoxication: Mechanisms, Effects, and Interventions. RESEARCH INVENTION JOURNAL OF SCIENTIFIC AND EXPERIMENTAL SCIENCES 3(1):12-20
